Publications

This study compares immune responses between ChAdOx1 (Adenovirus-based) and BNT162b2 (mRNA) COVID-19 vaccines. It finds that mRNA vaccines induce significantly higher memory B cell proliferation and longer-lasting antibody responses than Adenovirus vaccines, especially with extended dosing intervals.

This study explores how pre-vaccination HAI titres and vaccination history influence post-vaccine antibody responses in influenza vaccines. It finds that individuals with lower pre-vaccine antibody levels experience a larger and longer-lasting antibody boost after vaccination, while frequent vaccine recipients show a diminished response. The study emphasizes the importance of considering individual pre-vaccine antibody levels and vaccine history when interpreting post-vaccination antibody dynamics.

This study evaluates new RSV intervention strategies using mathematical modelling and economic analysis, highlighting the cost-effectiveness of seasonal programmes.

This study evaluates the cost-effectiveness of Nirsevimab intervention programmes for RSV prevention in England and Wales.

This study evaluates the epidemiological and cost-effectiveness impacts of mass paediatric influenza vaccination on existing elderly and risk-group programmes in England and Wales.