SARS-CoV-2

Memory B cell proliferation drives differences in neutralising responses between ChAdOx1 and BNT162b2 SARS-CoV-2 vaccines

This study compares immune responses between ChAdOx1 (Adenovirus-based) and BNT162b2 (mRNA) COVID-19 vaccines. It finds that mRNA vaccines induce significantly higher memory B cell proliferation and longer-lasting antibody responses than Adenovirus vaccines, especially with extended dosing intervals.

Risk factors for SARS-CoV-2 seroprevalence following the first pandemic wave in UK healthcare workers in a large NHS Foundation Trust

This study measures SARS-CoV-2 seroprevalence among UK healthcare workers following the first COVID-19 pandemic wave and explores risk factors and assay sensitivity.